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Production Supervision & Administration Measures

This page provides a plain English reference for production supervision & administration measures in China's medical device regulatory framework. Full content to be completed during editorial review.


Overview​

See MDSAR 2021 for the primary regulation. This page covers the implementing measure or standard listed above, explaining its scope, key requirements, and relationship to MDSAR 2021.


Official source​

Official texts are published on www.nmpa.gov.cn and the State Council website at www.gov.cn.

Disclaimer

Content on this site is written with AI assistance and is intended as a navigation aid only. Always verify against official NMPA sources before making regulatory decisions. Not affiliated with NMPA or any Chinese Government body. Not legal or regulatory advice.

Scope​

This measure implements MDSAR 2021 Chapter III (Articles 44-57), establishing requirements for medical device manufacturing, including production licensing, GMP compliance, quality management systems, and regulatory oversight.

Key Requirements​

  • Production licence required for Class II and III device manufacturers (Class I exempt)
  • GMP (Good Manufacturing Practice) compliance mandatory; QMS documentation required
  • Quality personnel: at least one qualified person responsible for quality
  • Batch record retention: minimum 5 years after device shelf life expiration
  • Change control procedures for manufacturing processes and facility modifications
  • Regular internal audits and management review of QMS
  • NMPA inspection authority: unannounced facility inspections permitted

Relationship to MDSAR 2021​

This measure operationalizes Article 44 (production licence) and Articles 47-49 (GMP and quality system) of MDSAR 2021 Chapter III with detailed procedural and technical requirements.